OR-043 UPRmt and mitophagy are selectively activated depending on muscle fiber types in insulin resistant rats
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چکیده
منابع مشابه
The Effect of Co-administration of Pioglitazone and Simvastatin on Insulin Resistance Parameters and PPAR.γ Expression in Insulin-resistant Rats
Backgrounds: Insulin resistance is a pathological condition associated with metabolic syndrome. In this condition, insulin action in liver, muscles, and adipocytes decreases which leads to hyperglycemia, hyperinsulinemia, and dyslipidemia. Thiazolidinediones (Pioglitazone) have been used to enhance insulin sensitivity but due to dyslipidemia associated with insulin resistance, ...
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Objective(s):In insulin resistance, the insulin action in liver, muscles and adipocytes decreases and result in hyperglycemia, dyslipidemia and hyperinsulinemia. In this study we evaluate the effect of Zataria multiflora extract on insulin sensitivity in high fructose fed insulin resistant rats, since this extract was shown antihyperglycemic effect in streptozotocin induced diabetes in rats. ...
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How skeletal muscles adapt to a repeated stimulus depends, to a large extent, on the inherent characteristics of the muscles themselves. Specifically, the types of fibers that make up individual muscles greatly influence the way your athletes will adapt to their training programs. There is a reason why some athletes can sprint faster and get bigger muscles more easily than others, and why some ...
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Objective(s): Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex proteins are involved in membrane trafficking. The expression of isoforms of SNAP-23, syntaxin-4, and VAMP-2 is significantly done in skeletal muscles; they control GLUT4 trafficking. It is believed that type 2 diabetes could be caused by the modifications in the express...
متن کاملPostexercise muscle glycogen resynthesis in obese insulin-resistant Zucker rats.
We determined the effect of an acute bout of swimming (8 x 30 min) followed by either carbohydrate administration (0.5 mg/g glucose ip and ad libitum access to chow; CHO) or fasting (Fast) on postexercise glycogen resynthesis in soleus muscle and liver from female lean (ZL) and obese insulin-resistant (ZO) Zucker rats. Resting soleus muscle glycogen concentration ([glycogen]) was similar betwee...
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ژورنال
عنوان ژورنال: Exercise Biochemistry Review
سال: 2018
ISSN: 2593-7588
DOI: 10.14428/ebr.v1i2.9723